Sculpher, M.

patient guideline health heterogeneity jurisdiction evaluation trial treatment effect study patient heterogeneity analysis transferability method model country estimate cost-effectiveness result resource use treatment effect resource difference baseline baseline risk decision value perindopril utility cost effectiveness event state source interest population disease issue effectiveness example article sculpher speci pharmacoeconomic preference characteristic unit costs practice europa parameter author subgroups input parameters review paper analyses subgroup regression approach research force policy adaptation university cost-effectiveness analysis evidence strati fied analyses technology input level ispor data transferability population reimbursement decisions heart modeling eq -5d generalizable treatment effects location artery disease table