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t-cell response patient vaccine antigen protein study peptide epitope t-cell responses infection sequence vaccination assay control hla-b autologou virus t cells interruption electroporated trial dendritic dendritic cells value mutation immunol cd 8+ t-cells el 9 epitope treatment interruption result elispot treatment /s tissue antigens allard count therapy number subject dc electroporated blood t-cell count study subject cytotoxic chimeric figure nef-specific t-cell responses t-cell counts e 11d replication recognition cd 4+ dc-based analysis mutant brussel ficiency point time points chimeric mrna hiv-speci nol 6 peptide encoding evolution plasma similarity phase clone cytokine autologous dc mrna encoding method proliferation molecule e 11d mutation ctl clone #59 universitair ziekenhuis brussel ifn -γ elisa hiv -1-infected patients antiretroviral therapy
4 Most Recent Publications
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Sequence evolution and escape from specific immune pressure of an HIV-1 Rev epitope with extensive sequence similarity to human nucleolar protein 6
(Article)
Goede, A.L. de Wal, A.C. van der Keersmaecker, B. de Heirman, C. Osterhaus, A.D.M.E. Thielemans, K. Allard, S.D. Gruters, R.A. Aerts, J.L. |
2012-03-01
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A phase I/IIa immunotherapy trial of HIV-1-infected patients with Tat, Rev and Nef expressing dendritic cells followed by treatment interruption
(Article)
Allard, S.D. Keersmaecker, B. de Padmos, I. Thielemans, K. Osterhaus, A.D.M.E. Lacor, P. Ende, M.E. van der Aerts, J.L. Baalen, C.A. van Gruters, R.A. Goede, A.L. de Verschuren, E.J. Koetsveld, J. Reedijk, M.L. Wylock, C. Beyer, W.E.Ph. Eilers, P.H. Corthals, J. |
2012-03-01
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P18-03. Dendritic cell-based immune therapy against HIV-1
(Article)
Gruters, R.A. Keersmaecker, B. de Osterhaus, A.D.M.E. Thielemans, K. Baalen, C.A. van Aerts, J.L. Goede, A.L. de Allard, S.D. Koetsveld, J. Corthals, J. Schutten, M. Heirman, C. Ende, M.E. van der Lacor, P. |
2009-10-22
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Functional T-cell responses generated by dendritic cells expressing the early HIV-1 proteins Tat, Rev and Nef
(Article)
Allard, S.D. Pletinckx, K. Thielemans, K. Aerts, J.L. Breckpot, K. Heirman, C. Bonehill, A. Michiels, A. Baalen, C.A. van Gruters, R.A. Osterhaus, A.D.M.E. Lacor, P. |
2008-07-04
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