Corrado, P.

disease patient amyloid prion mutation protein neuro fibrillary tangles amyloid angiopathy prion protein neuropathol prpsc brain cortex neuro fibrillary plaque y 226x mutation deposit codon antibody q 227x mutation ??? angiopathy phenotype patient 2 prion disease tangle dementia deposition fragment prp-caa blood vessels netherland prion protein gene creutzfeldt-jakob accumulation creutzfeldt-jakob disease amyloid depositions examination residue codon mutations month prion protein amyloidoses feature neuro fibrillary lesions multicentric amyloid plaques analysis blood patient 1 vessel prion diseases frontotemporal dementia disease duration staining formation section parchi neurology cerebellar tau accumulations variant centre lesion onset amyloid plaque formation anti-ab antibodies novel cerebellum symptom q 227x mutations clinicopathological phenotypes y 226x variant creutzfeldt-jakob disease paraf fin sections table neuropil threads haematoxylin – eosin change fi nding words duration