Jansen, C.

disease patient prion mutation amyloid protein cortex brain plaque prpsc neuro fibrillary tangles netherland neuropathol deposit prion protein antibody prion protein gene creutzfeldt-jakob disease amyloid angiopathy codon creutzfeldt-jakob fragment analysis dementia prion disease cerebellum phenotype neuro nding residue fibrillary accumulation y 226x mutation q 227x mutation ??? angiopathy patient 2 tangle frontotemporal dementia disease duration variant examination change deposition blot analysis fi ndings centre feature prp-caa gss disease copyright © 2011 blood vessels g 131v mutation prion diseases american association parchi blood association tau accumulations amyloid depositions american result neuropathologist codon mutations month prion protein amyloidoses jansen tissue gerstmann-straussler-scheinker ¨ disease spongiform neurol 8- kd fragment variant creutzfeldt-jakob disease +++ number striatum neuro fibrillary lesions study multicentric amyloid plaques identi fied