Hoppenbrouwers, I.A.

patient sclerosis study disease population association ms patients effect control susceptibility allele factor genet group family genome-wide level variant type 1 diabetes analysis hla-drb chapter result dutch neurol receptor function class locus expression region hoppenbrouwer diabetes 48 ms patients individual hintzen genetic relapse kinship erasmus univ rotterdam ratio number pathway evidence 24 ms patients replication smoking pregnancy imsgc table igfbp model onset pedigree ebers gc genealogical erasmu meta-analysi signi van duijn cm kif 1b summary significance relative cohort ancestor pathogenesis thyroid disease vitamin value igf-i erasmus mc il 7r transmission growth thyroid evi 5 rotterdam sclerosis genetics consortium neurology