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leukemia patient t-all lymphoblastic leukemia blood treatment analysis level lymphoblastic figure sample ptpn 2 disease trial protein study expression erasmus mc assessment mutation number result induction notch mrd assessment group fication european t-cell mantle cell lymphoma ba /f cells activation rq-pcr adult lymphoma protocol control transcript pathway oncogenic response relapse translocation jak 1 erasmu detection trials m bruggemann hematology childhood prognostic department therapy recombination diagnosis library monitoring cancer fl ow cytometry cell transplantation volume mrd status esg-mrd-all jak 1 mutations remission rearrangement signi quanti outcome mantle cytometry table target university point marker technique sensitivity standardization transplantation myc protein levels
6 Most Recent Publications
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TLX Homeodomain Oncogenes Mediate T Cell Maturation Arrest in T-ALL via Interaction with ETS1 and Suppression of TCRα Gene Expression
(Article)
Dadi, S. Noir, S. le Radford, I. Verhoeyen, E. Cosset, F.L. Petit, A. Ifrah, N. Dombret, H. Hermine, O. Spicuglia, S. Langerak, A.W. Macintyre, E. Payet-Bornet, D. Nadel, B. Ferrier, P. Asnafi, V. Lhermitte, L. Zacarias-Cabeza, J. Bergeron-Sawitzke, J. Villarese, P. Vachez, E. Dik, W.A. Millien, C. |
2012-04-17
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PTPN2 negatively regulates oncogenic JAK1 in T-cell acute lymphoblastic leukemia
(Article)
Kleppe, M. Soulier, J. Tartaglia, M. Foa, R. Macintyre, E. Haferlach, T. Cools, J. Asnafi, V. Mentens, N. Hornakova, T. Knoops, L. Constantinescu, S. Sigaux, F. Meijerink, J.P.P. Vandenberghe, P. |
2011-06-30
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Posttranscriptional deregulation of MYC via PTEN constitutes a major alternative pathway of MYC activation in T-cell acute lymphoblastic leukemia
(Article)
Bonnet, M. Loosveld, M. Mamessier, E. Roulland, S. Morgado, E. Formisano-Tréziny, C. Dik, W.A. Langerak, A.W. Prebet, T. Vey, N. Michel, G. Gabert, J. Montpellier, B. Soulier, J. Macintyre, E. Asnafi, V. Payet-Bornet, D. Nadel, B. Navarro, J.-M. Quilichini, B. Picard, C. Cristofaro, J.D. Bagnis, C. Fossat, C. Hernandez, L. |
2011-06-16
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Molecular remission is an independent predictor of clinical outcome in patients with mantle cell lymphoma after combined immunochemotherapy: A European MCL intergroup study
(Article)
Pott, C. Hoster, E. Dongen, J.J.M. van Klapper, W. Berger, F. Ribrag, V. Hoof, A.L. van Trneny, M. Walewski, J. Dreger, P. Unterhalt, M. Hiddemann, W. Delfau-Larue, M.H. Kneba, M. Kluin-Nelemans, H.C. Hermine, O. Macintyre, E. Dreyling, M. Beldjord, K. Böttcher, S. Asnafi, V. Plonquet, A. Siebert, R. Callet-Bauchu, E. Andersen, N. |
2010-04-22
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Standardized MRD quantification in European all trials: Proceedings of the second international symposium on MRD assessment in Kiel, Germany, 18-20 September 2008
(Article)
Brüggemann, M. Schrauder, A. Biondi, A. Cavé, H. Dombret, H. Fielding, A.K. Foà, R. Gökbuget, N. Goldstone, A.H. Goulden, N. Henze, G. Hoelzer, D. Raff, T. Janka-Schaub, G.E. Macintyre, E. Pieters, R. Rambaldi, A. Ribera, J.M. Schmiegelow, K. Spinelli, O. Stary, J. Stackelberg, A. von Kneba, M. Pfeifer, H. Schrappe, M. Dongen, J.J.M. van Dworzak, M.N. Ottmann, O.G. Asnafi, V. Baruchel, A. Bassan, R. Benoit, Y. |
2010-03-01
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Different chromosomal breakpoints impact the level of LMO2 expression in T-ALL
(Article)
Dik, W.A. Nadel, B. Langerak, A.W. Przybylski, G.K. Asnafi, V. Grabarczyk, P. Navarro, J.-M. Verhaaf, B. Schmidt, C.A. Macintyre, E. Dongen, J.J.M. van |
2007-07-01
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