Connolly, D.

cancer prostate prostate cancer study mortality screening population level patient death psa testing biopsy incidence prostate cancer mortality study entry testing treatment intervention prostate cancer incidence ireland baseline diagnosis serum control psa level result group difference cohort baseline serum psa serum psa level erspc cause detection country entry number ireland cancer registry reduction european control population follow-up trial intervention population european randomized study benefit trend therapy disease table health pca mortality psa screening increase metastasi registry pca metastasis antigen <.001 observation university signi netherland 1000 men survival prostatic analysis prostate-specific prostatic biopsies december signi ficantly regimen randomized prostate cancer screening pca-speci fic mortality baseline psa level grade dose-adjusted infusional cyclophosphamide prostate-speci risk-adjusted mortality outcomes