Vincken, W.

patient tiotropium ipratropium group difference analysis cost-effectiveness tiotropium group study ratio improvement exacerbation ipratropium group resource use resource health value sensitivity analysis treatment healthcare outcome disease number visit cost-effectiveness analysis treatment groups health outcomes cost-effectiveness ratios price trial sensitivity medication questionnaire healthcare costs george 9s effect evaluation dose inhaler hospital cost-effectiveness ratio respir netherland quality score table respiratory-related resource use j 667 dutch inpatient hospital days baseline uncertainty 0.27 threshold result unit costs threshold value inhaler oostenbrink imputation costeffectivenes author dyspnoea function george method trough fev 1 dutch unit costs proportion impact plane inpatient point estimate copd exacerbations period care unit base-case analysis baseline characteristics hospital admissions curve pharmacoeconomic