Diepstraten, H.J.A.

expression pre-b tumor c-myc lymphoma 2-gata gata 3 cd 2-gata notch 65ϫ/ϫ leukemia gata 3 expression 19arf cd 2-gata mice notch 1 transformation development protein level slp 65 mutation chain slp 65ϫ/ϫ mice t cell development p 19arf c-myc expression figure analysis ϫ/ϫslp transgene pre-b cell leukemia dp cells sample thymic selection p 53 protein result pathway number factor pre-b cell tumors slp 65ϫ/ϫ proliferation wild-type btk ϫ/ϫslp mice target transcription il -7r 65-de immunol activation cd 2-gata lymphomas cancer formation nding suppressor b-cell differentiation van hamburg pre-b cells blood thymocyte fi nding erasmus mc chromosome fi ndings n-myc slp 65-de mice cd 4 lineage fl ow cytometry cd 2-gata lymphoma thymic lymphomas p 53ϫ/ϫslp mice pre-bcr stage experiment vh 81x transgene p 19arf pathway notch 1 mutations oncogenic