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protein virus fluenza antibody vaccine titer glycan antigen infection fluenza virus expression group response preparation sh 53n animal hek 293t cells glycosylation replication result mannose hi antibody titers puri fied activity fluenza viruses hi titers vaccination immunization hemagglutinin glycoprotein signi terminal mannose moieties sh 53n preparations presence serum virology cell-produced sna 4 assay virol mhv infection vaccinated indomethacin neuraminidase effect control level inhibitor number adjuvant immunity hek 293t cell-produced iscom matrix m moietie chain sh 53n proteins strain sample glcnac 2 cells binding study sequence system domain n-glycan glycosylation state virus replication antigenic panel signi ficantly culture state mouse figure terminal glcnac residues endoh glycosylation states protection
3 Most Recent Publications
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Glycan-dependent immunogenicity of recombinant soluble trimeric hemagglutinin
(Article)
Vries, R.P. de Smit, C.H. Koopmans, M.P.G. Rottier, P.J.M. Haan, C.A.M. de Bruin, E. de Rigter, A. Cornelissen, L.A.H.M. Eggink, D. Chung, N.P.Y. Moore, J.P. Sanders, R.W. Hokke, C.H. |
2012-11-01
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Recombinant soluble, multimeric HA and NA exhibit distinctive types of protection against pandemic swine-origin 2009 A(H1N1) influenza virus infection in ferrets
(Article)
Bosch, B.J. Bodewes, R. Vries, R.P. de Kreijtz, J.H.C.M. Bartelink, W. Amerongen, G. van Rimmelzwaan, G.F. Haan, C.A.M. de Osterhaus, A.D.M.E. Rottier, P.J.M. |
2010-10-01
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Cyclooxygenase activity is important for efficient replication of mouse hepatitis virus at an early stage of infection
(Article)
Raaben, M. Einerhand, A.W.C. Taminiau, L.J.A. Houdt, M. van Bouma, J. Raatgeep, R.H. Büller, H.A. Haan, C.A.M. de Rossen, J.W. |
2007-06-25
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