Kreijl, C.F. van

repair cancer ttd mice patient wild-type csb / mice mouse defect tumor csb / transcription syndrome fibroblast uv-induced mutation xeroderma pigmentosum hoeijmaker xeroderma carcinogenesi skin cancer wild-type mice sensitivity predisposition pigmentosum trichothiodystrophy csb-deficient mice csb-deficient synthesis exposure feature model cockayne lesion ttd patients csb / fibroblasts figure ner-deficient rna synthesis ttd mefs genome repair uv sensitivity lehmann cancer predisposition disorder effect protein sarasin allele vermeulen experiment bootsma genome uv-induced inflammation table stefanini csb mice ttd cells survival difference protocol hyperplasia study mouse model analysis ner-deficient mice repair defect susceptibility strand cs patients p 53 gene skin cancer predisposition xpdr 722w allele weeda group ttd repair defect fragment animal cancer proneness genotoxic sensitivity genet