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pathway leukemia lucena hh pathway hedgehog figure resistance chemoresistance k 562 cells leukemia kcs queiroz inhibitor k 562 level expression vincristine myeloid inhibition hh inhibitors cancer treatment hh pathway components phenotype hh pathway activity mtt reduction assays gli 1 oncogene cyclopamine queiroz myeloid leukemia chemotherapeutic drugs chemotherapy -30 activation assay leukemic hh pathway inhibitors effect vitamin 4 1 c glc 4-doxo cells chemotherapy-resistant phenotype mdr phenotype protein gant 61 component activity mechanism antibody transfected tumor study speci fic gfp-only transfected cells mitoxantrone concentration lauth cell viability expression levels doxorubicin drug resistance multidrug resistance hh inhibition vincristine-induced cell death mdr leukemia 14 000 g multidrug viability smom 2-gfp suf ficient therapy vincristine treatment smom 2-gfp cells mdr leukemia cells hematopoietic overexpression center buffer target chemosensitization presence
1 Most Recent Publications
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Hedgehog signaling maintains chemoresistance in myeloid leukemic cells
(Article)
Queiroz, K.C.S. Ruela-de-Sousa, R.R. Fuhler, G.M. Aberson, H.L. Ferreira, C.V. Peppelenbosch, M.P. Spek, C.A. |
2010-12-02
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