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Spek, C.A.

( C.A. Spek)


pathway cancer hh pathway tumor patient resistance inhibitor hedgehog level leukemia study therapy treatment protein activation inhibition hscrp hscrp levels lucena expression medulloblastoma hiv-infected patients mutation mechanism pancreatic factor queiroz disease figure marker activity chemoresistance basal cell carcinoma k 562 cells leukemia kcs queiroz metastatic group k 562 development target gli 1 hh pathway inhibitors antagonist inflammation cyclopamine combination chemotherapy hiv-infected hh inhibition effect research vincristine abc use gemcitabine regimen category model response molecule myeloid epithelial drug resistance antiretroviral therapy coagulation pancreatic cancer hh inhibitors stromal growth von willebrand factor progression state result assay aids research sauvage fication abacavir combination therapy infarction 2009.




3 Most Recent Publications

Targeting Hedgehog signaling and understanding refractory response to treatment with Hedgehog pathway inhibitors (Article)
Queiroz, K.C.S. Spek, C.A. Peppelenbosch, M.P.
2012-08-01
Hedgehog signaling maintains chemoresistance in myeloid leukemic cells (Article)
Queiroz, K.C.S. Ruela-de-Sousa, R.R. Fuhler, G.M. Aberson, H.L. Ferreira, C.V. Peppelenbosch, M.P. Spek, C.A.
2010-12-02
Markers of inflammation and coagulation indicate a prothrombotic state in HIV-infected patients with long-term use of antiretroviral therapy with or without abacavir (Article)
Jong, E. Meijers, J.C.M. Gorp, E.C.M. van Spek, C.A. Mulder, J.W.
2010-04-16