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globin locus expression transcription signal result mouse region chromatin effect level figure transcriptional position analysis transcript liver probe control erythroid globin genes grosveld model protein element number deletion activation transgene mechanism promoter wijgerde interaction erythroid cells fragment factor p-globin globin gene regulation blood development chapter hybridization liver cells globin locus structure heterochromatin competition adult percentage transcript signals chromatin structure sequence intron dnase study experiment distance hypersensitive fraser dillon frequency binding gene expression activity elongation histone function p gene embo j p-globin locus y genes globin gene expression initiation minute b globin locus 11.5 chromosome assay change
7 Most Recent Publications
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Activation of the beta β globin locus by transcription factors and chromatin modifiers.
(Article)
McMorrow, T. Wijngaard, A. van den Trimborn, T. Lohuizen, M. van Jenuwein, T. Djabali, M. Philipsen, J.N.J. Fraser, P. Grosveld, F.G. Milot, E. |
2000-01-01
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Mechanisms of developmental control of transcription in the murine alpha- and beta-globin loci
(Article)
Trimborn, T. Gribnau, J.H. Fraser, P. Grosveld, F.G. |
1999-01-01
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Chromatin interaction mechanism of transcriptional control in vivo.
(Article)
Gribnau, J.H. Boer, E. de Trimborn, T. Wijgerde, M.G.J.M. Milot, E. Fraser, P. Grosveld, F.G. |
1998-10-15
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Transcriptional regulation of the B-Globin locus: of mice and men
(Doctoral Thesis)
Trimborn, T. |
1998-09-11
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The effect of distance on long-range chromatin interactions.
(Article)
Dillon, N. Trimborn, T. Strouboulis, J. Fraser, P. Grosveld, F.G. |
1997-01-01
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The dynamics of gene expression: frequency and duration of transcription.
(Article)
Milot, E. Strouboulis, J. Fraser, P. Trimborn, T. Wijgerde, M.G.J.M. Boer, E. de Langeveld, A. Tan-Un, K. Vergeer, W. Yannoutsos, N. Grosveld, F.G. |
1996-10-01
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The role of EKLF in human β-globin gene competition.
(Article)
Wijgerde, M.G.J.M. Gribnau, J.H. Trimborn, T. Nuez, B. Philipsen, J.N.J. Grosveld, F.G. Fraser, P. |
1996-01-01
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