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chromosome expression x chromosome globin figure transcription locus result signal region chromatin analysis mouse rnf 12 factor inactivation erythroid es cells x chromosomes differentiation number level promoter probe control development liver protein hlr 5 cells study sequence initiation activation model mechanism domain element embryo deletion interaction x chromosome inactivation transcript probability allele blood xist expression intron transcriptional experiment regulation adult stage s-phase nature percentage process globin genes es cell lines effect erythroid cells grosveld x inactivation function histone day 3 panel liver cells murine xist rna dnase cycle binding cell lines presence transition change genet beta-globin wijgerde hybridization
10 Most Recent Publications
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Different flavors of X-chromosome inactivation in mammals
(Article)
Dupont, C. Gribnau, J.H. |
2013-04-09
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The Pluripotency Factor-Bound Intron 1 of Xist Is Dispensable for X Chromosome Inactivation and Reactivation In Vitro and In Vivo
(Article)
Minkovsky, A. Barakat, T.S. Sellami, N. Chin, M. Gunhanlar, N. Gribnau, J.H. Plath, K. |
2013-03-22
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Precise BAC targeting of genetically polymorphic mouse ES cells
(Article)
Barakat, T.S. Rentmeester, E. Sleutels, F. Grootegoed, J.A. Gribnau, J.H. |
2011-10-01
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The inactive X chromosome adopts a unique three-dimensional conformation that is dependent on Xist RNA
(Article)
Splinter, D. Wit, E. de Laat, W.L. de Nora, E.P. Klous, P. Werken, H.J.G. van de Zhu, Y. Kaaij, L.J.T. IJcken, W.F.J. van Gribnau, J.H. Heard, E. |
2011-07-01
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Xist regulation and function eXplored
(Article)
Pontier, D.B. Gribnau, J.H. |
2011-05-31
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RNF12 activates Xist and is essential for X chromosome inactivation
(Article)
Barakat, T.S. Gunhanlar, N. Pardo, C. G. Achame, E.M. Ghazvini, M. Boers, R. Kenter, A. Rentmeester, E. Grootegoed, J.A. Gribnau, J.H. |
2011-02-15
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RNF12 activates Xist and is essential for X chromosome inactivation
(Article)
Barakat, T.S. Gunhanlar, N. Pardo, C. G. Achame, E.M. Ghazvini, M. Boers, R. Kenter, A. Rentmeester, E. Grootegoed, J.A. Gribnau, J.H. |
2011-02-15
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Evaluating the relationship between spermatogenic silencing of the X chromosome and evolution of the Y chromosome in chimpanzee and human
(Article)
Achame, E.M. Baarends, W.M. Gribnau, J.H. Grootegoed, A.J. |
2010-12-01
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A key commitment step in erythropoiesis is synchronized with the cell cycle clock through mutual inhibition between PU.1 and S-phase progression
(Article)
Pop, R. Shearstone, J.R. Shen, Q. Liu, Y. Hallstrom, K. Koulnis, M. Gribnau, J.H. Socolovsky, M. |
2010-09-01
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A murine ESC-like state facilitates transgenesis and homologous recombination in human pluripotent stem cells
(Article)
Buecker, C. Chen, H.H. Geijsen, N. Polo, J.M. Daheron, L. Bu, L. Barakat, T.S. Okwieka, P. Porter, A. Gribnau, J.H. Hochedlinger, K. |
2010-06-04
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