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replication rad 51ap protein repair recombination damage formation figure rad 51 dna damage checkpoint es cells response polymerase dna replication wild-type replication forks hydroxyurea strand cycle mrad 175 pathway result magda-thesis.indd 2/22/08 loop formation structure wild-type es cells mrad 17 activity lesion rad 17 dna repair phase 81es cells substrate 81à/à es cells binding analysis mechanism dna replication forks agent endonuclease treatment h 2ax foci mouse rad 54 template control cerevisiae molecule synthesis mitomycin c chapter number chromosomal interaction mitomycin replication fork activation dsb formation embo j function break dna synthesis junction yeast dna lesions cell cycle progression experiment tls polymerases phosphorylation kinase j biol chem genomic recovery process aphidicolin cell cycle radiation
6 Most Recent Publications
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Mechanisms of dealing with DNA damage-induced replication problems
(Article)
Budzowska, M. Kanaar, R. |
2009-01-01
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Cellular Responses to Replication Problems
(Doctoral Thesis)
Budzowska, M. |
2008-03-26
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RAD51AP1 Is a Structure-Specific DNA Binding Protein that Stimulates Joint Molecule Formation during RAD51-Mediated Homologous Recombination
(Article)
Modesti, M. Budzowska, M. Baldeyron, C. Demmers, J.A. Ghirlando, R. Kanaar, R. |
2007-11-09
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The structure-specific endonuclease Mus81 contributes to replication restart by generating double-strand DNA breaks
(Article)
Hanada, K. Budzowska, M. Davies, S.L. Drunen, E. van Onizawa, H. Beverloo, H.B. Maas, A. Essers, J. Hickson, I.D. Kanaar, R. |
2007-11-01
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Mutation of the mouse Rad17 gene leads to embryonic lethality and reveals a role in DNA damage-dependent recombination.
(Article)
Budzowska, M. Jaspers, I. Hoeijmakers, J.H.J. Maas, A. Essers, J. Waard, H. de Drunen, E. van Hanada, K. Beverloo, H.B. Hendriks, R.W. Klein, J.E.M.M. de Kanaar, R. |
2004-09-01
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The structure-specific endonuclease Ercc1-Xpf is required to resolve DNA insterstrand cross-link-induced double-strand breaks
(Article)
Niedernhofer, L.J. Odijk, H. Kanaar, R. Budzowska, M. Drunen, E. van Maas, A. Theil, A.F. Wit, J. de Beverloo, H.B. Hoeijmakers, J.H.J. Jaspers, N.G.J. |
2004-01-01
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