Fritsche, L.G.

study age-related macular degeneration photoreceptor region disease macular age-related expression retina degeneration factor smoking status smoking analysis frequency effect binding mouse cis-regulatory control apolipoprotein association university table genome haplotype research sequence allele transcription group status signi variation age group apolipoprotein e gene department element model crx binding nrl à/à retinas ficant level diplotype activity ophthalmol promoter wild-type rho-cbr institute center genotype health kingdom distribution crx sites crx-bound regions crx binding sites cis-regulatory elements downloaded genet apolipoprotein e apoe allele frequencies population laboratory chip-seq number swaroop interaction crx-bound nrl à/à retina mckay smoker london hospital mutation network -ε3/g disease genes gender