Chen, Z.

carnitine cisplatin octn 2 wild-type mice cancer transporter transport wild-type mouse octn 2 research cation expression nephrotoxicity kidney cisplatin-induced administration mouse study change slc 22a carnitine homeostasis cancer research carnitine transport excretion cisplatin administration function cisplatin treatment acid oxidation mechanism cancer research downloaded acetylcarnitine american oct 1 oct 2 carnitine deficiency cisplatin nephrotoxicity inhibition onlinefirst animal sample association treatment september analysis pcdna 3 vector downregulation protein downloaded octn 2 function copyright receptor level urine october number transfected article effect homeostasi substrate uptake factor lancaster peroxisome baseline agent cation /carnitine transporter control oxidation patient clin cancer res result deficiency cation transporter 2 model carnitine-shuttle genes 0.05 error bars pharmacol mutation