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leukemia tlx 1 t-all analysis patient tumor mouse expression trisomy aberration group myeloid leukemia bcl 11b 1-induced study table number karyotype mutation myeloid prognostic tlx 1-transgenic mice survival result children blood bcl 11b mutations mitotic t cell transformation control mitotic checkpoint cancer university signi trisomy 19 1-transgenic thymocyte oncology erasmus mc department research outcome checkpoint nature encoding model center trisomy 8 cytogenetic preleukemic prognostic signi ficance figure lymphoblastic leukemia transformation sample factor deletion chromosomal tlx 1-induced leukemias 11 q 23/mll treatment presence speci alteration 23/mll hematology target cytogenetic aberrations t cell development prognostic factor lymphoblastic tlx 1-induced tumors bcl 11b locus abnormality translocation trial cohort acgh analysis sirna
2 Most Recent Publications
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Prognostic significance of additional cytogenetic aberrations in 733 de novo pediatric 11q23/MLL-rearranged AML patients: Results of an international study
(Article)
Coenen, E.A. Raimondi, S. Hasle, H. Harrison, C.J. Heerema, N.A. Kaspers, G.J. Leszl, A. Litvinko, N. Nigro, L.L. Morimoto, A. Perot, C. Auvrignon, A. Harbott, J. Reinhardt, D. Rubnitz, J.E. Smith, F.O. Stary, J. Stasevich, I. Strehl, S. Taga, T. Tomizawa, D. Webb, D. Zemanová, Z. Zimmermann, M. Alonzo, T.A. Pieters, R. Zwaan, C.M. Heuvel-Eibrink, M.M. van den Beverloo, H.B. Chang, M. Creutzig, U. Dworzak, M.N. Forestier, E. Gibson, B. |
2011-06-30
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The TLX1 oncogene drives aneuploidy in T cell transformation
(Article)
Keersmaecker, K. de Real, P.J. Hadler, M. Lenz, J. Aplan, P.D. Kelliher, M. Kee, B.L. Pandolfi, P.P. Kappes, D. Gounari, F. Petrie, H. Meulen, J. van der Gatta, G.D. Speleman, F. Paietta, E. Racevskis, J. Wiernik, P.H. Rowe, J. Soulier, J. Avran, D. Cavé, H. Dastugue, N. Raimondi, S. Palomero, T. Meijerink, J.P.P. Cordon-Cardo, C. Califano, A. Ferrando, A.A. Sulis, M.L. Tosello, V. Vlierberghe, P. van Barnes, K. Castillo, M. Sole, X. |
2010-11-01
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