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patient mucosal healing bowel healing mucosal bowel preservation disease treatment fliximab preservation ni -0401 therapy study crohn -0401 remission group expert panel consensus response trial panel expert number surgery survey table placebo level endoscopic score antibody hospitalization round flammation factor delphi t cells certolizumab pegol tnf antagonists volume endoscopy baseline abbott result modulation flammatory bowel disease fication antagonist tcr-cd 3 cytokine cytokine release placebo group t-cell steering committee effect anti-cd meeting population netherland certolizumab safety topic gastroenterology disease course infusion bowel function randomized fliximab treatment adalimumab cd 3 modulation week 6 fi rst patient quanti fication course 10 mg pegol outcome centocor complication
2 Most Recent Publications
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Recommendations for the treatment of Crohn's disease with tumor necrosis factor antagonists: An expert consensus report
(Article)
Feagan, B.G. Lémann, M. Silverberg, M. Sorrentino, D. Woude, C.J. van der Vermeire, S. Rutgeerts, P. Befrits, R. Connell, W. D'Haens, G. Ghosh, S. Michetti, P. Ochsenkühn, T. Panaccione, R. Schreiber, S. |
2012-01-01
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Phase I, double-blind, randomized, placebo-controlled, dose-escalation study of NI-0401 (a fully human anti-CD3 monoclonal antibody) in patients with moderate to severe active Crohn's disease
(Article)
Woude, C.J. van der Stokkers, P.C.F. Dijkstra, G. Jong, D.J. de Oldenburg, B. Farhan, M. Richard, T. Dean, Y. Hommes, D.W. Bodegraven, A.A. van Assche, G. van Hebzda, Z. Paradowski, L. D'Haens, G. Ghosh, S. Feagan, B. Rutgeerts, P. |
2010-10-01
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