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disease patient mutation study alzheimer allele dementia genotype family polymorphism control association analysis onset genet frequency apolipoprotein group region population table linkage chromosome protein rotterdam carrier atherosclerosi subject sequence effect university department research carotid presenilin plaque model duijn number early-onset artery level netherland rotterdam study score marker alzheimer disease psen 1 amyloid apoe genotype population-based carotid artery atherosclerosis result family history intron autosomal factor brain van duijn cm carotid arteries apoe genotypes sample apoe *4 evidence late-onset promoter individual neurology reference hofman genetic prion protein gene cholesterol e 3e group apolipoprotein e polymorphism apolipoprotein e neurol broeckhoven late-onset alzheimer app 692 mutation
10 Most Recent Publications
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Linkage and association studies identify a novel locus for Alzheimer disease at 7q36 in a Dutch population-based sample
(Article)
Rijk, P. de Cruts, M. Swieten, J.C. van Aulchenko, Y.S. Rademakers, R. Broeck, M. van den Broeckhoven, C. van Sleegers, K. Dermaut, B. Theuns, J. Weckx, S. Duijn, C.M. van Pooter, T. Corsmit, E. Del-Favero, J. |
2005-01-01
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Familial clustering and genetic risk for dementia in a genetically isolated Dutch population.
(Article)
Sleegers, K. Forey, F. Duijn, C.M. van Broeckhoven, C. van Theuns, J. Aulchenko, Y.S. Rademakers, S. Cruts, M. Gool, W.A. van Heutink, P. Oostra, B.A. Swieten, J.C. van |
2004-07-01
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Absence of pathogenic mutations in presenilin homologue 2 in a conclusively 17-linked tau-negative dementia family
(Letter To Editor)
Rademakers, R. Broeck, M. van den Sleegers, K. Duijn, C.M. van Broeckhoven, C. van Cruts, M. |
2004-02-01
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Octapeptide repeat insertions in the prion protein gene and early onset dementia
(Article)
Croes, E.A. Houwing-Duistermaat, J.J. Sleegers, K. Forey, F. Harten, B. van Cruts, M. Duijn, C.M. van Theuns, J. Swieten, J.C. van Broeckhoven, C. van |
2004-01-01
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Early cognitive decline is associated with prion protein codon 129 polymorphism
(Letter To Editor)
Croes, E.A. Dermaut, B. Houwing-Duistermaat, J.J. Broeck, M. van den Cruts, M. Breteler, M.M.B. Hofman, A. Broeckhoven, C. van Duijn, C.M. van |
2003-08-01
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Apolipoprotein E4 in the temporal variant of frontotemporal dementia
(Letter To Editor)
Rosso, S.M. Roks, G. Broeckhoven, C. van Cruts, M. Duijn, C.M. van Swieten, J.C. van |
2002-06-05
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Apolipoprotein E4 in the temporal variant of frontotemporal dementia
(Article)
Rosso, S.M. Forey, F. Cruts, M. Duijn, C.M. van Swieten, J.C. van Heutink, P. Broeckhoven, C. van |
2002-01-01
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The gene encoding nicastrin, a major gamma-secretase component, modifies risk for familial early-onset Alzheimer disease in a Dutch population-based sample
(Article)
Dermaut, B. Theuns, J. Broeckhoven, C. van Sleegers, K. Hasegawa, H. Vennekens, K. Corsmit, E. St George-Hyslop, P.H. Cruts, M. Duijn, C.M. van Broeck, M. van den |
2002-01-01
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Amyloid beta secretase gene (BACE) is neither mutated in nor associated with early-onset Alzheimer's disease
(Article)
Cruts, M. Dermaut, B. Rademakers, R. Roks, G. Munteanu, G. Duijn, C.M. van Broeck, M. van den Broeckhoven, C. van |
2001-11-02
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Influence of the prion protein and the apolipoprotein E genotype on the Creutzfeldt-jakob Disease phenotype
(Article)
Everbroeck, B. van Croes, E.A. Pals, P. Dermaut, B. Jansen, G. Duijn, C.M. van Cruts, M. Broeckhoven, C. van Martin, J-J. Cras, P. |
2001-11-02
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