Straetemans, G.C.M.

tumor t cells antigen therapy cancer response melanoma tcr t cells receptor expression tcr gene therapy patient transfer study immunol treatment target model mouse figure lymphocytes chapter blood tcr-engineered t cells tumor cells t cell responses hla-a chain t cell therapy persistence result metastatic melanoma transgene anti-tumor il -15 vector rosenberg sa rosenberg strategy clone cytokine metastatic domain peptide tcr gene transfer t-cell trial memory t lymphocytes surface yang jc activation level t cell activation hla-a 2 antibody tcrab production immunotherapy number debet function mouse t cells tumor-specific tcr-engineered restifo np combination t cell transfer car t cells flow cytometry chimeric molecule regression efficacy t cell persistence activity antigen-specific mage-a 100/a wunderlich jr