Mazzarella, L.

jarid jarid 2 es cells target wild-type information differentiation analysis mouse promoter wild-type es cells 2-2 antibody 0.0 experiment level mouse es cells protein nkx 2‑2 locus right 2-deficient prc 1 figure expression -/- prc 2 control –jarid enrichment panel histone polycomb publisher ezh 2 macmillan suz 12 nkx 2-2 locus 2× flag –jarid bivalent region lamin prc 2 components oct 4 development binding 1.0 input component number chromatin transcription 0.5 locus nature target genes 2.0 result bivalent genes primer knockout 2–/– blot analysis chip experiments transcriptional cell extracts biology 8+/+ +/+ allele results show 8–/– nanog fig . 4b jarid 2-deficient cells immunoprecipitation 1.5 h 3k levels distance millipore percentage