Trucco, M.

islet transplantation monkey blood xenotransplantation pig islets alemtuzumab porcine complement islet transplantation c-peptide transplant antibody expression insulin level factor graft figure organ porcine islets activation group effect response ibmir depletion diabetes tissue number cynomolgus monkeys cynomolgu therapy pittsburgh primates plasma glucose coagulation survival study result primate t-cell pancreatic cooper xenograft heart function liver rejection blood cells reaction islet tx windt anti-cd non-human primates islet damage lymphocyte depletion university treatment pancreatic islets model exposure nonhuman animal xenogeneic antigen administration anti-cd 154 mab repopulation release patient fl ow cytometry damage memory lymph nodes baboon cooper dkc heparin lymphocyte