Bruggeman, F.J.

system design concentration control equation model receptor ligand parameter enzyme nucleus network biology reaction figure pathway membrane function analysis rate equations import importin ficient protein approach systems biology transport westerhoff response process behavior molecule signal value plasma membrane transcriptional response component state parameter values property principle cytoplasm export modeling mechanism 2010 embo transcriptional macmillan publishers number rate equation binding cargo plasma k m j design principles ratio diffusion control analysis 123 systems biology activity rangtp transduction figure 2 g change diffusion coef ficient design 6 core-nr figure 2 interaction aspect silico snoep localization exportin metabolite product figure 2 b solution signal transduction thermodynamic