Doornbos, G.

outbreak cluster surveillance signal syndromic disease syndromic surveillance cluster-signal detection analysis legionnaire window cause figure influenza recurrence interval hospitalization study analyses number setting netherland health table statistic lri-cluster $5 yr time window activity level period alarm diagnose pathogen patient threshold figure 2 coverage april hospital 7 weeks result $1 yr lri clusters non-restrictive parameter settings syndrome permutation scan statistic proportion study period infection decline lowerrespiratory infections 1 year method computation time disease outbreaks discharge significance www.plosone.org population volume criteria lri-outbreak issue 25 km york city influenza season hospital discharge diagnoses scan-statistic scan statistic parameter syndromic data outbreak detection influenza activity satscan macro accessory data artifact recurrence interval scan statistics control