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locus expression b-globin transcription globin 8 c 3/c chromatin chromosome b-globin locus region interaction level mouse study gene expression 8 c 3–c liver factor erythroid probe element control looping promoter organization enhancer analysis contact e 14.5 figure beta-globin b-globin lcr chromatin looping activation 14.5 position protein β- globin locus dna elements b-globin genes globin genes factory transcription factories sequence genome regulation locus control region hlcr-a association interchromosomal frequency β h 1 grosveld number erythroid cells genes dev technology chromatin hub distance ectopic lcr transcription factors gene-dense region genomic result signal integration image 3 c technology genet nature binding function histone effect 4 c technology transcriptional chromosomal difference ensmusg erythroid differentiation
4 Most Recent Publications
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Variegated gene expression caused by cell-specific long-range DNA interactions
(Article)
Noordermeer, D. Wit, E. de Klous, P. Werken, H.J.G. van de Simonis, M. Lopez-Jones, M. Eussen, B.H.J. Klein, J.E.M.M. de Singer, R.H. Laat, W.L. de |
2011-08-01
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Joining the loops: β-globin gene regulation
(Article)
Noordermeer, D. Laat, W.L. de |
2008-12-01
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Transcription and chromatin organization of a housekeeping gene cluster containing an integrated β-globin locus control region
(Article)
Noordermeer, D. Branco, M.R. Splinter, D. Klous, P. IJcken, W.F.J. van Swagemakers, S.M.A. Koutsourakis, M. Spek, P.J. van der Pombo, A. Laat, W.L. de |
2008-03-01
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Three-Dimensional Organization of Gene Expression in Erythroid Cells
(Article)
Laat, W.L. de Klous, P. Kooren, J.A. Noordermeer, D. Palstra, R.J.T.S. Simonis, M. Splinter, D. Grosveld, F.G. |
2008-02-18
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