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scopus: 7403221562

Silva, A.J.

(Alcino Silva)


nf 1+/à mice simvastatin group gaba release neuron children baseline placebo synapsin acamkii phosphorylation figure 12 weeks result score release treatment control trial training neuro wt mice mipsc effect study synapsin i phosphorylation synapsin i frequency measure analysis outcome neurofibromatosis type 1 mutant 12.5 mm kcl level outcome measures neurofibromatosi deletion number mipsc frequency neuro fibromin fibromin morris water maze performance quadrant plasticity synaptic nf 1 gene increase signi hippocampal value nf 1dlx placebo groups placebo group simvastatin group inhibition nf 1 mice water presynaptic picrotoxin mouse model memory conditioning patient erasmus mc signi ficantly augmentation acamkii-t kushner 1acamkii ± sem object assembly test acamkii-ko mice object vesicle assembly target quadrant acamkii-ko fi ndings




3 Most Recent Publications

Neurofibromin Regulation of ERK Signaling Modulates GABA Release and Learning (Article)
Cui, Y. Costa, R.M. Murphy, G.G. Elgersma, Y. Zhu, Y. Gutmann, D.H. Parada, L.F. Mody, I. Silva, A.J.
2008-10-31
Effect of simvastatin on cognitive functioning in children with neurofibromatosis type 1: A randomized controlled trial (Article)
Krab, L.C. Goede-Bolder, A. de Silva, A.J. Zeeuw, C.I. de Moll, H.A. Elgersma, Y. Aarsen, F.K. Pluijm, S. Bouman, M.J. Geest, J.N. van der Leguin, M. Catsman, C. Arts, W.F.M. Kushner, S.A.
2008-07-16
Kinase activity is not required for αCaMKII-dependent presynaptic plasticity at CA3-CA1 synapses (Article)
Hojjati, M.R. Woerden, G.M. van Tyler, W.J. Giese, K.P. Silva, A.J. Pozzo-Miller, L. Elgersma, Y.
2007-09-01