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expression globin sequence fragment mouse probe result level footprint deletion region promoter number protein grosveld adult p-globin tissue position analysis research p-globin gene liver m r n activity y-globin clone stage acids research yolk sac transcription element core fragment control chromosome nature enhancer binding expression level brain nuclease cosmid nf-e 2 copy number mel cells globin gene figure erythroid y-globin gene neurofilament hypersensitive breakpoint development cluster transgene globin genes hybridization factor blood /3- filament sample u.s.a library nucleotide hybridized addition /3- globin gene / biochimica family event fetus deletion event 1-6 effect foetal liver copy numbers restriction foetal study
10 Most Recent Publications
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Transcriptional Activation by hypersensitive site three of the human β-globin Locus Control Region in murine erythroleukemia cells.
(Article)
Pruzina, S. Antoniou, M. Hurst, J. Grosveld, F.G. Philipsen, J.N.J. |
1994-10-18
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DNaseI hypersensitive sites 1, 2 and 3 of the human β-globin dominant control region directs position-independent expression.
(Article)
Fraser, P. Hurst, J. Collis, P. Grosveld, F.G. |
1990-01-01
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The Regulation of expression of human β-globin genes. UCLA Symposia (Proceedings) on Molecular and Cellular Biology. "Molecular Approaches to Developmental Biology".
(In Book)
Grosveld, F.G. Antoniou, M. Boer, E. de Habets, G. Hurst, J. Kollias, G. MacFarlane, F. Wrighton, N. |
1987-01-01
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The human neurofilament gene (NEFL) is located on the short arm of chromosome 8.
(Article)
Hurst, J. Flavell, D. Julien, J-P. Meijer, D.N. Mushynski, W. Grosveld, F.G. |
1987-01-01
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A tissue and developmental specific enhancer is located downstream from the human β-globin gene.
(Article)
Kollias, G. Hurst, J. Boer, E. de Grosveld, F.G. |
1987-01-01
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Cloning and developmental expression of the murine neurofilament gene family.
(Article)
Julien, J-P. Meijer, D.N. Flavell, D. Hurst, J. Grosveld, F.G. |
1986-01-01
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Regulated expression of human A γ-, β-, and hybrid γ β-globin genes in transgenic mice: manipulation of the developmental expression patterns.
(Article)
Kollias, G. Wrighton, N. Hurst, J. Grosveld, F.G. |
1986-01-01
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γδβ-thalassaemias 1 and 2 are the result of a 100 kpb deletion in the human β-globin cluster.
(Article)
Taramelli, R. Kioussis, D. Vanin, E. Bartram, K. Groffen, J. Hurst, J. Grosveld, F.G. |
1986-01-01
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Chromosomal localization of the human Thy-1 gene.
(Article)
Rijs, J. van Giguere, V. Hurst, J. Agthoven, A.J. van Goyert, S. Grosveld, F.G. Geurts van Kessel, A.H.M. |
1985-01-01
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Structure and Expression of the human globin genes and murine histocompatibility antigen genes.
(In Proceedings)
Flavell, R.A. Grosveld, F.G. Simpson, E. James, R. Townsend, A.R.M. Taylor, P.M. Schmidt, W. Ferluga, J. Leben, L. Santamaria, M. Atfield, G. Festenstein, H. Busslinger, M. Boer, E. de Kioussis, D. Mellor, A.L. Golden, L. Weiss, E. Hurst, J. Bud, H. Bullman, H. |
1983-01-01
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