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Pandolfi, P.P.

( P.P. Pandolfi)


tlx 1 analysis t-all mouse tumor clone expression leukemia es cell clones table mutation bcl 11b 1-induced euploid es cells tlx 1-transgenic mice number chimaera metaphase bcl 11b mutations mitotic t cell transformation germline control mitotic checkpoint nature 1-transgenic thymocyte culture es cell clone passage checkpoint result encoding chimaerism preleukemic chromosome euploid metaphases lymphoblastic leukemia blastocyst transformation sample deletion chimaeric chromosomal tlx 1-induced leukemias presence cancer embryo alteration development target t cell contribution lymphoblastic tlx 1-induced tumors bcl 11b locus research center acgh analysis sirna abnormality percentage university model enrichment chromosomally tissue columbia university irl press ltd right t cell progenitors all-sil tlx 1 overexpression tlx 1-induced transformation es cellembryo chimaera medicine oncogene karyotype cell cycle analysis




3 Most Recent Publications

The TLX1 oncogene drives aneuploidy in T cell transformation (Article)
Keersmaecker, K. de Real, P.J. Hadler, M. Lenz, J. Aplan, P.D. Kelliher, M. Kee, B.L. Pandolfi, P.P. Kappes, D. Gounari, F. Petrie, H. Meulen, J. van der Gatta, G.D. Speleman, F. Paietta, E. Racevskis, J. Wiernik, P.H. Rowe, J. Soulier, J. Avran, D. Cavé, H. Dastugue, N. Raimondi, S. Palomero, T. Meijerink, J.P.P. Cordon-Cardo, C. Califano, A. Ferrando, A.A. Sulis, M.L. Tosello, V. Vlierberghe, P. van Barnes, K. Castillo, M. Sole, X.
2010-11-01
The chromosome make-up of mouse embryonic stem cells is predictive of somatic and germ cell chimerism. (Article)
Longo, L. Bygrave, A. Grosveld, F.G. Pandolfi, P.P.
1997-01-01
Targeted disruption of the housekeeping gene encoding glucose 6-phosphate dehydrogenase (G6PD-null): G6PD is dispensable for pentose synthesis but essential for defense against oxidative stress. (Article)
Pandolfi, P.P. Sonati, F. Rivi, R. Mason, P. Grosveld, F.G. Luzzatto, L.
1995-01-01