Ribeiro de Almeida, C.

expression gata 3 cd 2-gata gata 3 expression 2-gata locus differentiation region igk locus pre-b figure pre-b cells 17 differentiation culture transcription 17 cells interaction il -4 17 cultures 1-cre immunol analysis cytokine development production recombination enhancer factor segment immunity flow cytometric analysis presence level 0.0 number vk gene segments effect vh 81x intracellular ficient pro-b element t cells usage control information fig 220+cd signi il -17-producing cells il -171 cells germline 1.0 -17 induction ctcf-de rearrangement absence 0.5 b cell development nding il -2 production igk enhancer interactions rt-pcr anti-il germline transcription signi ficantly value vk region b cells 1.5 fraction erasmus mc rotterdam cd 2-gata transgene -10 chromatin vk usage proportion -17-producing t-cell nfatc