Hiemstra, P.S.

airway asthma muscle inspiration patient protein uepx /c subject methacholine muscle bundles resistance study expression children respir signi biopsy fev 1 flammation eosinophil protein x airway hyperresponsiveness eosinophil inspiration –induced bronchodilation sputum bundle breath effect hyperresponsivenes marker desmin signi ficantly correlation muscle cells bronchodilation function physiol relationship type iii collagen level contractile expiratory resistance challenge control subjects lung function extracellular matrix proteins –induced result response department airway responses matrix number disease muscle area change lamina propria pd 20 methacholine extracellular a-sm-actin figure group control reduction allergy pc 20 methacholine nitric oxide inhalation elastin journal fi bronectin bronchodilatory effect university expiratory calponin section measurement mast cells extracellular matrix flammatory mch inhalation