Bygrave, A.

clone es cell clones euploid es cells chimaera metaphase germline culture es cell clone passage table analysis number chimaerism chromosome euploid metaphases blastocyst mouse chimaeric embryo contribution abnormality percentage chromosomally tissue irl press ltd es cellembryo chimaera karyotype es cell lines aneuploidy bradley karyotype analysis injection robertson chimaeric mouse chimaeric mice germ cell chimaerism ability totipotency n.o.a euploid cells aneuploid formation natl acad capacity presence experiment vector transmission level blot analysis passage 15 euploid clones adult recombined tables 1 pandolfi adult chimaera chromosome make-up es cell line capecchi cytogenetic cytogenetic analysis table 1 es cell culture hydrocephalu selection euploidy teratocarcinoma make-up region nature method mutation murine cellembryo order recombination unmanipulated thoma