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patient hsp 60 muscle disease response muscle tissue tissue cytokine dm patients control muscle biopsy samples protein sample blood stimulation production antigen biopsy study disease remission remission cytokine production expression il -10 mycobacterial self hsp 60 arthritis dermatomyositi analysis t cells prakken self antigens inflammation muscle biopsy tissues t cell targets 60. target proliferative medium -10 epitope figure hsp 60. patient 2 disease activity autoantigen t cell responses autoreactive t cells t cell proliferation utrecht netherland muscle disease stimulation index patient 1 ifn ␥ muscle weakness 2 patients control subjects control subject 96 hours subject shock activation blood samples heat-shock proteins proinflammatory reaction result culture university difference heat-shock children antibody stress berent j 22 study patients finding t cell reactivity utrecht university
1 Most Recent Publications
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Hsp60 in inflamed muscle tissue is the target of regulatory autoreactive T cells in patients with juvenile dermatomyositis
(Article)
Elst, E.F. Klein, M. Jager, W. de Kamphuis, S.S.M. Wedderburn, L.R. Zee, R. van der Albani, S. Kuis, W. Prakken, B.J. |
2008-02-01
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