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repair liver tumor mouse csbm /m mice cancer mutation damage xpdttd −/− protein xpc à/à mice level figure dna damage control growth nucleotide excision repair animal life span phenotype defect response excision xpdttd mice oxidative dna repair ficient tissue metabolism xpa à/à mice van steeg model nucleotide csbm /m expression transcription frequency syndrome pathway analysis wild-type gg-ner study xpa −/− mice van der horst csbm /m pups result group table ageing c 57bl background apoptosi cockayne cockayne syndrome factor csb −/− mice xpa à/à tc-ner lung tumors research development survival xpc −/− mice number death wijnhoven patient increase wk-old cancer res xeroderma pigmentosum steeg oxidative metabolism signi ficantly spleen d-old hoeijmaker category
4 Most Recent Publications
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Homeostatic imbalance between apoptosis and cell renewal in the liver of premature aging XpdTTD mice
(Article)
Park, J.Y. Cho, M.O. Hoeijmakers, J.H.J. Cohen, P. Vijg, J. Suh, Y. Leonard, S. Calder, B. Mian, I.S. Kim, W.H. Wijnhoven, S.W.P. Steeg, H. van Mitchell, J.R. Horst, G.T.J. van der |
2008-06-11
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Mouse models for xeroderma pigmentosum group A and group C show divergent cancer phenotypes
(Article)
Melis, J.P.M. Wijnhoven, S.W.P. Steeg, H. van Beems, R.B. Roodbergen, M. Berg, J. van den Moon, H. Friedberg, E.C. Horst, G.T.J. van der Hoeijmakers, J.H.J. Vijg, J. |
2008-03-01
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Tissue specific mutagenic and carcinogenic responses in NER defective mouse models
(Article)
Wijnhoven, S.W.P. Hoogervorst, E.M. Waard, H. de Horst, G.T.J. van der Steeg, H. van |
2007-01-03
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Impaired genome maintenance suppresses the growth hormone--insulin-like growth factor 1 axis in mice with Cockayne syndrome.
(Article)
Pluijm, I. van der Garinis, G.A. Niedernhofer, L.J. Velasco, S. Friedberg, E.C. Tanaka, K. Steeg, H. van Hoeijmakers, J.H.J. Horst, G.T.J. van der Brandt, R.M.C. Gorgels, T.G.M.F. Wijnhoven, S.W.P. Diderich, K. Wit, J. de Mitchell, J.R. Oostrom, C.T.M. van Beems, R.B. |
2006-12-12
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