Kumanduri, V.

bone mineral density density mineral fracture cohort study association allele osteoporosis risk alleles femoral neck replication genome-wide osteoporotic osteoporotic fracture e ffect spine rotterdam risk allele osteoporotic fractures tnfrsf 11b rotterdam cohort femoral expression lrp 5 twinsuk tnfrsf twinsuk discovery cohort genome-wide association study lymphoblast cell lines replication cohorts value osteoprotegerin fracture risk analysis identi variant rs 3736228 chingford women e ffects discovery research rs 4355801 p value www.thelancet.com vol 371 genotyping genome-wide association scan risk factors polymorphism sample population stage disease identi fied webtable nucleotide polymorphisms table genet individual genome factor tnfrsf 11b gene number genome-wide signi ficance lrp 5 gene johansson h allelic receptor chromosomal position article miner people european fragility fractures lymphoblast www.thelancet.com nucleotide fferent participant