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patient trial event eptifibatide infarction stroke thrombocytopenia investigator pursuit platelet death study treatment 30 days table /iiia site investigators syndrome outcome group end-point baseline placebo therapy pursuit trial nonhemorrhagic stroke effect incidence enzyme glycoprotein elevation angina nonhemorrhagic population state end point treatment effect heparin model strategy point committee ischemic result heart site investigator califf rm revascularization ck-mb reduction intervention event rates circulation adjudication definition mahaffey infusion 72 hours swets subs service randomized topol ej assessment receptor percutaneou america events committee disagreement nadir review criteria count integrilin therapy enzyme elevations receptor suppression europe propensity score enrolment blood propensity adjudicated
7 Most Recent Publications
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Systematic adjudication of myocardial infarction end-points in an international clinical trial.
(Article)
Mahaffey, K.W. Harrington, R.A. Corbalon, R. Lee, K.L. Deckers, J.W. Simoons, M.L. Topol, E.J. Califf, R.M. Akkerhuis, K.M. Kleiman, N.S. Berdan, L.G. Crenshaw, B.S. Tardiff, B.E. Granger, C.B. Jong, I. de Bhapkar, M. Widimsky, P. |
2001-09-04
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Disagreements between central clinical events committee and site investigator assessments of myocardial infarction end-points in an international clinical trial: review of the PURSUIT study
(Article)
Mahaffey, K.W. Harrington, R.A. Corbalon, R. Lee, K.L. Deckers, J.W. Simoons, M.L. Topol, E.J. Califf, R.M. Akkerhuis, K.M. Kleiman, N.S. Berdan, L.G. Crenshaw, B.S. Tardiff, B.E. Granger, C.B. Jong, I. de Bhapkar, M. Widimsky, P. |
2001-09-04
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Early percutaneous coronary intervention, platelet inhibition with eptifibatide, and clinical outcomes in patients with acute coronary syndromes. PURSUIT Investigators
(Article)
Kleiman, N.S. Cokkinos, D.V. Berdan, L.G. Lorenz, T.J. Boersma, H. Simoons, M.L. Harrington, R.A. Califf, R.M. Topol, E.J. Lincoff, A.M. Flaker, G.C. Pieper, K.S. Wilcox, R.G. |
2000-01-01
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Management of patients with acute coronary syndromes in the United States by platelet glycoprotein IIb/IIIa inhibition
(Article)
Lincoff, A.M. Guerci, A.D. Berdan, L.G. Harrington, R.A. Califf, R.M. Hochman, J.S. Ohman, E.M. Pepine, C.J. Topol, E.J. Kopecky, S.L. Kleiman, N.S. Simoons, M.L. Pacchiana, C.M. Kitt, M.M. |
2000-01-01
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Clinical Significance of Thrombocytopenia During a Non-ST-Elevation Acute Coronary Syndrome
(Article)
McClure, M.W. Berkowitz, S.C. Simoons, M.L. Topol, E.J. Califf, R.M. Harrington, R.A. Deckers, J.W. Karsch, K. Sparapani, R. Tguttle, R. Kleiman, N.S. Berdan, L.G. Lincoff, A.M. Diaz, R. Gretler, D. Kitt, M.M. |
1999-01-01
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Stroke in Patients With Acute Coronary Syndromes: Incidence and Outcomes in the Platelet Glycoprotein IIb/IIIa in Unstable Angina: Receptor Suppression Using Integrilin Therapy (PURSUIT) Trial
(Article)
Mahaffey, K.W. MacAulay, C.M. Miller, J.M. Sloan, M.A. Berdan, L.G. Lincoff, A.M. Deckers, J.W. Harrington, R.A. Simoons, M.L. Granger, C.B. Califf, R.M. Graffagnino, C. Alberts, M.J. Laskowitz, D.T. Topol, E.J. |
1999-01-01
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A comparison of directional atherectomy with coronary angioplasty in patients with coronary artery disease
(Article)
Topol, E.J. Leya, F. King 3rd, S.B. Daniel, B. Mark, D.B. Isner, J.M. Holmes Jr, D.R. Ellis, S.G. Lee, K.L. Keeler, G.P. Berdan, L.G. Hinohara, T. Pinkerton, C.A. Califf, R.M. Whitlow, P.L. Hofling, B. Simonton, C.A. Masden, R.R. Serruys, P.W.J.C. Leon, M.B. Williams, D.O. |
1993-01-01
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