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protein repair substrate damage binding hhr 23b hhr 23 proteins xpc-hr 23b nucleotide nucleotide excision repair lesion mhr 23b excision strand tfiih interaction activity mhr 23b mice figure reaction antibody ssdna hoeijmaker result mhr 23b / xpc-hr analysis factor presence function hhr 23a dna damage replication domain development xeroderma single-stranded pigmentosum mouse recognition nuclease sugasawa genome fraction mhr 23a region panel mechanism group embryo wild-type number buffer defect ercc 1xpf xpc –hr 1–xpf complex cancer replication protein downloaded effect xpc protein amount gg-ner molecule transcription ercc 1–xpf incision dna repair ubiquitin level polarity coli ssb protein assay system proteasome formation extract hanaoka
10 Most Recent Publications
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UV-DDB-dependent regulation of nucleotide excision repair kinetics in living cells
(Article)
Nishi, R. Alekseev, S. Dinant, C. Hoogstraten, D. Houtsmuller, A.B. Hoeijmakers, J.H.J. Vermeulen, W. Hanaoka, F. Sugasawa, K. |
2009-06-04
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Fluorescence correlation spectroscopy of the binding of nucleotide excision repair protein XPC-hHr23B with DNA substrates
(Article)
Roche, Y. Zhang, D. Segers-Nolten, G.M. Vermeulen, W. Wyman, C. Sugasawa, K. Hoeijmakers, J.H.J. Otto, C. |
2008-09-01
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A novel regulation mechanism of DNA repair by damage-induced and RAD23-dependent stabilization of xeroderma pigmentosum group C protein.
(Article)
Ng, J.M.Y. Vermeulen, W. Horst, G.T.J. van der Bergink, S. Sugasawa, K. Vrieling, H. Hoeijmakers, J.H.J. |
2003-07-01
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DNA bending by the human damage recognition complex XPC-HR23B.
(Article)
Janicijevic, A. Sugasawa, K. Shimizu, Y. Hanaoka, F. Wijgers, N. Djurica, M. Hoeijmakers, J.H.J. Wyman, C. |
2003-03-01
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Developmental defects and male sterility in mice lacking the ubiquitin-like DNA repair gene mHR23B
(Article)
Ng, J.M.Y. Vrieling, H. Hoeijmakers, J.H.J. Horst, G.T.J. van der Sugasawa, K. Ooms, M.P. Grootegoed, J.A. Vreeburg, J.T.M. Visser, P. Beems, R.B. Gorgels, T.G.M.F. Hanaoka, F. |
2002-02-05
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Developmental defects and male sterility in mice lacking the ubiquitin-like DNA repair gene mHR23B.
(Article)
Ng, J.M.Y. Vrieling, H. Hoeijmakers, J.H.J. Horst, G.T.J. van der Sugasawa, K. Ooms, M.P. Grootegoed, J.A. Vreeburg, J.T.M. Visser, P. Beems, R.B. Gorgels, T.G.M.F. Hanaoka, F. |
2002-01-01
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Novel functional interactions between nucleotide excision DNA repair proteins influencing the enzymatic activities of TFIIH, XPG, and ERCC1-XPF
(Article)
Winkler, G.S. Sugasawa, K. Eker, A.P.M. Laat, W.L. de Hoeijmakers, J.H.J. |
2001-01-09
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Interaction of hHR23 with S5a. The ubiquitin-like domain of hHR23 mediates interaction with S5a subunit of 26 S proteasome
(Article)
Hiyama, H. Yokoi, M. Masutani, C. Sugasawa, K. Maekawa, T. Tanaka, K. Hanaoka, F. Hoeijmakers, J.H.J. |
1999-01-01
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Xeroderma pigmentosum group C complex is the initiator of global genome repair.
(Miscellaneous)
Sugasawa, K. Ng, J.M.Y. Masutani, C. Spek, P.J. van der Eker, A.P.M. Hanaoka, F. Bootsma, D. Hoeijmakers, J.H.J. |
1998-08-01
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DNA-binding polarity of human replication protein A positions nucleases in nucleotide excision repair.
(Article)
Laat, W.L. de Appeldoorn, E. Sugasawa, K. Jaspers, N.G.J. Hoeijmakers, J.H.J. |
1998-01-01
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