Mierlo, G. van

level patient -12 complement activation csf levels il -12 meningiti children complement activation shock admission nonsurvivor 1-inh disease survivor plasma protein c 4bp cytokine parameter complex capillary leakage production correlation tumor necrosis factor interleukin immunol elastase pathway control blood study lactoferrin concentration leakage sepsis -10 hospital il -10 pneumococcal meningitis factor purpura system complement activation products table meningococcal result capillary product il -6 elisa crp levels control subjects group trinchieri difference serum complement system inhibitor 3-crp release c 1-inh response c 3b levels sophia children regression circle relation ic 1-inh severity sample interferon range subject mortality meningococcal disease value killer cell lactate