Voort, E. van der

level patient infant activation flt 3 complement pkc 412 sample leukemia mutation blood expression flt 3 expression infant mll samples inhibitor infant mll patients study complement activation children shock infant mll nonsurvivor 1-inh disease protein survivor plasma c 4bp flt 3 phosphorylation germline mll genes parameter kinase complex flt 3 inhibition concentration receptor infant mll cells capillary leakage difference leukemic cells group noninfant figure wild-type flt 3 flt 3l expression inhibition admission elastase pathway leukemic hospital myeloid leukemia cytotoxic response tyrosine flt 3 gene lactoferrin sepsis leakage result lymphoblastic lymphoblastic leukemia correlation analysis purpura cytotoxic complement activation products wild-type flt 3 inhibitors system mll gene rearrangements meningococcal 3/itd capillary jm domain product crp levels rearrangement phosphorylation activation loop il -6