Oosterom, A. van

patient imatinib smoking study cancer t cells grade pharmacokinetic transplantation effect cyp 1a smoker infection ebv-speci group reactivation treatment hospital response transplant nonsmokers exposure epstein –barr virus sarcoma failure ebv dna load month cyp 3a –barr epstein analysis disease ebv infection toxicity research bone sarcoma group australia virus stromal therapy stromal tumours imatinib mesylate t-cell progression european cell transplantation population trial speci survival gist patients blood protein novarti clearance center netherland department stromal tumors event eortc smoking status recipient phase tissue sample metabolism pharmacol university utrecht mesylate perforin lymphoproliferative problem european organisation interaction article epitope van baarle 45 patients