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scopus: 7004775266

Ploemacher, R.E.

(Robert Ploemacher)


marrow stromal blood hematopoietic number bone marrow hemopoietic mouse liver culture study erythroblast erythroid activity macrophage tissue effect spleen clone erythropoiesi colony factor ercc 1à/à mice progenitor gata -2 / progenitors stromal clones differentiation microenvironment expression adult control proliferation treatment stromal cell lines embryo figure patient analysis gata -2 ploemacher level assay hemopoiesi hsc activity stromal cells experiment seeding efficiency system observation anemia concentration seeding /scid reticular cells organ murine growth transplantation membrane erythropoietin precursor nod /scid mice support recipient result formation production bfu-e change g-csf hematopoietic progenitors electron medium increase protein frequency cell lines receptor efficiency




10 Most Recent Publications

Reduced hematopoietic reserves in DNA interstrand crosslink repair- deficient Ercc1-/- mice. (Article)
Prasher, J.M. Lalai, A.S. Heijmans-Antonissen, C. Ploemacher, R.E. Hoeijmakers, J.H.J. Touw, I.P. Niedernhofer, L.J.
2005-02-23
GATA-2 plays two functionally distinct roles during the ontogeny of hematopoietic stem cells (Article)
Ling, K-W. Ottersbach, K. Hamburg, J.P. van Oziemlak, A. Tsai, F.Y. Orkin, S.H. Ploemacher, R.E. Hendriks, R.W. Dzierzak, E.A.
2004-01-01
Stromal cell lines from mouse aorta-gonads-mesonephros subregions are potent supporters of hematopoietic stem cell activity (Article)
Oostendorp, R.A. Harvey, K.N. Kusadasi, N. Bruijn, M.F.T.R. de Saris, C. Ploemacher, R.E. Medvinsky, A.L. Dzierzak, E.A.
2002-01-01
Embryonal subregion-derived stromal cell lines from novel temperature-sensitive SV40 T antigen transgenic mice support hematopoiesis (Article)
Oostendorp, R.A. Dzierzak, E.A. Saris, C. Medvinsky, A.J. Kusadasi, N. Nakayama, N. Harvey, K. Orelio, C. Ottersbach, K. Covey, T. Ploemacher, R.E.
2002-01-01
Connexin-43 gap junctions are involved in multiconnexin-expressing stromal support of hemopoietic progenitors and stem cells (Article)
Cancelas, J.A. Koning, A.E. de Mayen, A.E. Rombouts, E.J. Ploemacher, R.E. Koevoet, J.L.M.
2000-01-01
Comparison of different busulfan analogues for depletion of hematopoietic stem cells and promotion of donor-type chimerism in murine bone marrow transplant recipients (Article)
Westerhof, G.R. Ploemacher, R.E. Boudewijn, A. Blokland, I. Dillingh, J.H. McGown, A.T. Hadfield, J.A. Dawson, M.J. Down, J.D.
2000-01-01
Sustained receptor activation and hyperproliferation in response to granulocyte colony-stimulating factor (G-CSF) in mice with a severe congenital neutropenia/acute myeloid leukemia-derived mutation in the G-CSF receptor gene (Article)
Hermans, M.H. Heijmans-Antonissen, C. Ward, A.C. Mayen, A.E. Ploemacher, R.E. Touw, I.P.
1999-01-01
Seeding efficiency of primitive human hematopoietic cells in nonobese diabetic/severe combined immune deficiency mice: implications for stem cell frequency assessment (Article)
Hennik, P.B. van Koning, A.E. de Ploemacher, R.E.
1999-01-01
An in vitro model for cytogenetic conversion in CML. Interferon-alpha preferentially inhibits the outgrowth of malignant stem cells preserved in long-term culture (Article)
Cornelissen, J.J. Ploemacher, R.E. Wognum, B.W. Borsboom, A. Kluin-Nelemans, H.C. Hagemeijer, A. Löwenberg, B.
1998-01-01
Defective haematopoiesis in fetal liver resulting from inactivation of the EKLF gene. (Article)
Nuez, B. Michalovich, D. Bygrave, A. Ploemacher, R.E. Grosveld, F.G.
1995-01-01