Healy, D.G.

patient mutation lrrk 2 2019ser disease idiopathic pd parkinson symptom idiopathic study lrrk 2-associated pd neurology onset centre frequency university carrier family department estimate research penetrance consortium stage qsbb series lrrk 2 mutations series group hospital institute 10 years fference scale london analysis prevalence 79 years disorder parkinsonism ffected grant 2-associated method cause treatment population tremor article pd onset 69 years duration testing disease duration di fference dystonia health progression incidence symptom onset control individual genetic table non-motor symptoms foundation state 40 years 59 years penetrance estimates clinic kaplan-meier hoehn sample medicine university college london qsbb group queen square park 2 mutations york state department fi ve patients