Williams, D.R.

patient mutation disease r-tau lrrk 2 4 r-tau 2019ser parkinson control idiopathic pd isoform cohort neurology study symptom centre arti ficial csf idiopathic neurochemistry © 2012 supranuclear palsy university brain sample level assay signi lrrk 2-associated pd ratio analysis onset neurochemistry institute buffer disorder frequency 3 r-tau value authors journal carrier dementia family department sample dilution buffer concentration signi ficantly estimate alzheimer corticobasal degeneration research penetrance author strip t-tau supranuclear ficial tau isoforms consortium qsbb series palsy stage 10 pg /ml p-tau cerebrospinal fl uid group 4 r-tau isoforms series lrrk 2 mutations hospital diagnosis 10 years protein difference fference tauopathie neurochem figure pathology criteria corticobasal scale