Pisarski, P.

tacrolimu cyp 3a patient cyp 3a genotype cyp 3a expressers transplantation genotype cyp 3a nonexpressers transplant cyp 3a allele concentration nonexpresser study rejection transplant recipients expresser allele recipient tacrolimus dose tacrolimus dose requirement exposure incidence pharmacokinetic pharmacogenetic analysis kidney target tacrolimus c 0 tacrolimus pharmacokinetics day 3 difference month polymorphism tacrolimus exposure effect result cyp 3a individuals predose target concentrations group clearance function william lippincott pharmacogenetic substudy kidney transplant recipients genomic tacrolimus predose concentrations wilkin creatinine clearance dose-adjusted influence article therapy model interval dose-corrected creatinine outcome reproduction immunoassay confidence table fdcc study drug monitoring corticosteroids individual cytochrome abcb 1 genotype graft cyp 3a protein liver 10 ng /ml addition trial cyp 3a genotypes van gelder t requirement cyp 3a need copyright