Honkoop, P.

patient lamivudine hepatitis treatment hepatitis b therapy virus study level liver hbv-dna mitochondrial replication hbeag serum infection activity month lamivudine therapy schalm sw resistance hepatitis b virus group toxicity analogue man ra mutation nucleoside hepatitis b infection combination interferon hbv-dna levels flare nucleoside analogues disease result assay effect schalm polymerase lamivudine treatment university hospital rotterdam figure withdrawal seroconversion analysis response 6 months table trial mitochondrial toxicity hbeag seroconversion fialuridine liver disease a-ifn hepatology lamivudine resistance type b hepatitis hepatitis b patients monotherapy hepatocyte biopsy hbv replication period enzyme dna levels antigen clearance suppression histological event baseline motif limit failure liver biopsy abbott detection hepatitis flare hybridization