View Author

Hanscombe, O.

( O. Hanscombe)


globin expression population figure fragment level region grosveld probe mel cells number hypersensitive 8- globin gene mouse clone analysis tk-neo minilocu transfected hss 4 deletion copy number transcription binding p-globin expression levels control erythroid factor thy-l sequence tk-neo gene 3-globin locus antoniou 6- globin gene promoter globin genes globin gene hss 2 hypersensitive sites nuclease protection analysis b-globin k 562 cells panel acids research effect l cells protein thy-l gene oligonucleotide 0.3 kollia l cell populations k 562 populations dnaasel transgene f 3-globin gene induction result erythroid cells oligo 0.2 table dnasei presence dna samples tissue acids res hypersensitive site p-globin gene binding sites enhancer activity 6- globin microlocu nuclease sample hybridized stage




5 Most Recent Publications

Importance of globin gene order for correct developmental expression. (Article)
Hanscombe, O. Whyatt, D. Fraser, P. Yannoutsos, N. Greaves, D.R. Dillon, N. Grosveld, F.G.
1991-01-01
Hypersensitive site 4 of the human β-globin locus control region. (Article)
Pruzina, S. Hanscombe, O. Whyatt, D. Grosveld, F.G. Philipsen, J.N.J.
1991-01-01
The regulation of human globin gene switching. (In Book)
Fraser, P. Talbot, D. Philipsen, J.N.J. Pruzina, S. Antoniou, M. Lindenbaum, M.H. Hanscombe, O. Dillon, N. Grosveld, F.G.
1991-01-01
The β-globin dominant control region activates homologous and heterologous promoters in a tissue-specific manner (Article)
Blom van Assendelft, M. Hanscombe, O. Grosveld, F.G. Greaves, D.R.
1989-01-01
High-level, erythroid specific, expression of the human α-globin gene in transgenic mice and the production of human haemoglobin in murine erythrocytes. (Article)
Hanscombe, O. Vidal, M. Kaeda, J. Luzzatto, L. Greaves, D.R. Grosveld, F.G.
1989-01-01