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leukemia mutation expression aberration myeloid leukemia mef 2c patient probe t-all figure myeloid table subtype cluster study cytogenetic group 3-itd 2-1 analysis cancer probe sets flt 3-itd identi fied sample blood cohort type-i children nkx 2-1 type-ii aberrations type-ii identi value rearrangement event prognostic validation cohort cebpa lymphoblastic leukemia type-i aberrations discriminative probe sets 75 probe sets mll-rearranged adult validation j clin oncol result factor signature gene expression signature subgroups proliferative mll-rearranged aml oncogene outcome mef 2c expression gene expression profiles level microarray t-all cases npm 1 mutations number discovery cohort discriminative gene expression frequency classifier cytogenetic subtypes flt 3 haematologica oncogenic mll-ptd accuracy wt 1 mutations lmo 2 method tandem duplication control balgobind
3 Most Recent Publications
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Integrative analysis of type-I and type-II aberrations underscores the genetic heterogeneity of pediatric acute myeloid leukemia
(Article)
Balgobind, B.V. Hollink, I.H.I.M. Zemanová, Z. Stary, J. Cayuela, J.M. Baruchel, A. Creutzig, U. Reinhardt, D. Pieters, R. Michel Zwaan, C. Heuvel-Eibrink, M.M. van den Arentsen-Peters, S.T.C.J.M. Zimmermann, M. Harbott, J. Beverloo, H.B. Bergh, A.R.M. von Cloos, J. Kaspers, G.J. Haas, V. de |
2011-10-01
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Integrated Transcript and Genome Analyses Reveal NKX2-1 and MEF2C as Potential Oncogenes in T Cell Acute Lymphoblastic Leukemia
(Article)
Homminga, I. Pieters, R. Vlierberghe, P. van Ferrando, A.A. Cayuela, J.M. Verhaaf, B. Beverloo, H.B. Horstmann, M. Haas, V. de Wiekmeijer, A.-S. Pike-Overzet, K. Staal, F.J.T. Langerak, A.W. Laat, W.L. de Soulier, J. Sigaux, F. Meijerink, J.P.P. Rooi, J.J. de Stubbs, A. Verstegen, M.M.A. Vuerhard, M.J. Buijs-Gladdines, J.G.C.A.M. Kooi, C. Klous, P. |
2011-04-12
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Evaluation of gene expression signatures predictive of cytogenetic and molecular subtypes of pediatric acute myeloid leukemia
(Article)
Balgobind, B.V. Heuvel-Eibrink, M.M. van den Cayuela, J.M. Baruchel, A. Meyer, C. Marschalek, R. Trka, J. Stary, J. Beverloo, H.B. Pieters, R. Zwaan, C.M. Boer, M.L. den Menezes, R.X. de Reinhardt, D. Hollink, I.H.I.M. Arentsen-Peters, S.T.C.J.M. Wering, E.R. van Kaspers, G.J. Cloos, J. Bont, E.S.J.M. de |
2011-02-01
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