Laan, J.W. van der

behaviour brain morphine activity effect abstinence injection concentration gaba-t inhibition morphine abstinence behaviour gaba-ergic ssa-dh mechanism system action level quasi-morphine abstinence behaviour increase administration reaction enzyme gaba concentration rat brain behavioural pharmacal study result locomotor activity inhibitor compound quasi-morphine neurochem glutamate abstinence behaviour value receptor number nerve withdrawal cm-pf bruinvel experiment syndrome y-aminobutyric 2-0 g dpa-induced release animal gaba-ergic activity 15 min substrate symptom sodium y-aminobutyric acid table brain res dpa-induced behaviour score locus coeruleus succinic semialdehyde dehydrogenase metabolism biochem time course degradation control dependence compartment terminal abstinence score locus coeruleu locomotor suppression 0.5 period robert maitre glial cells amygdala