Burgess, A.

transcript clone genomic sequence region marker c 7orf candidate library identi analysis identi fied polymorphic markers c 7orf transcripts polymorphic contig ppd candidate region cosmid chromosome c 7orf transcript protein hlxb 9 gene candidate genes fication nucleotide mutation genomic contig ppd phenotype candidate region function genomic dna polydactyly primer table fragment recombination ampli fied family ampli receptor brain selection product yac clones cosmid clones identi fication mutation analysis hsc 7e locus centromeric side polydactyly locus individual zgurica phenotype p 1 libraries tissue hybridization encode 5ј race experiments nylon fi lters position 450 kb sequence alterations centromeric cdna libraries recombination event pcr products genet genomic clones preaxial event cdna selection preaxial polydactyly heutink malformations method dutch vector sequencing screening